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Gut Inflammation Induced by Dextran Sulfate Sodium Exacerbates Aβ Plaque Deposition in the App(NL-G-F) Mouse Model of Alzheimer’s Disease

BACKGROUND: Although it is known that the brain communicates with the gastrointestinal (GI) tract via the well-established gut-brain axis, the influence exerted by chronic intestinal inflammation on brain changes in Alzheimer’s disease (AD) is not fully understood. We hypothesized that increased gut...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Sohrabi, Mona, Pecoraro, Heidi L., Combs, Colin K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8122495/
https://ncbi.nlm.nih.gov/pubmed/33427741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-201099
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