NMDAR-dependent long-term depression is associated with increased short term plasticity through autophagy mediated loss of PSD-95

Long-term depression (LTD) of synaptic strength can take multiple forms and contribute to circuit remodeling, memory encoding or erasure. The generic term LTD encompasses various induction pathways, including activation of NMDA, mGlu or P2X receptors. However, the associated specific molecular mecha...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Compans, Benjamin, Camus, Come, Kallergi, Emmanouela, Sposini, Silvia, Martineau, Magalie, Butler, Corey, Kechkar, Adel, Klaassen, Remco V., Retailleau, Natacha, Sejnowski, Terrence J., Smit, August B., Sibarita, Jean-Baptiste, Bartol, Thomas M., Perrais, David, Nikoletopoulou, Vassiliki, Choquet, Daniel, Hosy, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8121912/
https://ncbi.nlm.nih.gov/pubmed/33990590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23133-9
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