HNF1A regulates colorectal cancer progression and drug resistance as a downstream of POU5F1

POU5F1-expressing cells can self-renew and differentiate, contributing to metastasis formation in colorectal cancer (CRC), but it plays an important role in normal pluripotent stem cells. Here, we identified the CRC-specific gene, HNF1A, which is the downstream of POU5F1. HNF1A associates with fatty...

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Vydáno v:Sci Rep
Hlavní autoři: Fujino, Shiki, Miyoshi, Norikatsu, Ito, Aya, Yasui, Masayoshi, Matsuda, Chu, Ohue, Masayuki, Uemura, Mamoru, Mizushima, Tsunekazu, Doki, Yuichiro, Eguchi, Hidetoshi
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8121855/
https://ncbi.nlm.nih.gov/pubmed/33990627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89126-2
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