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Crystal structure of SARS-CoV-2 Orf9b in complex with human TOM70 suggests unusual virus-host interactions

Although the accessory proteins are considered non-essential for coronavirus replication, accumulating evidences demonstrate they are critical to virus-host interaction and pathogenesis. Orf9b is a unique accessory protein of SARS-CoV-2 and SARS-CoV. It is implicated in immune evasion by targeting m...

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Библиографические подробности
Опубликовано в: :Nat Commun
Главные авторы: Gao, Xiaopan, Zhu, Kaixiang, Qin, Bo, Olieric, Vincent, Wang, Meitian, Cui, Sheng
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2021
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8121815/
https://ncbi.nlm.nih.gov/pubmed/33990585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23118-8
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