A framework for highly multiplexed dextramer mapping and prediction of T cell receptor sequences to antigen specificity

T cell receptor (TCR) antigen–specific recognition is essential for the adaptive immune system. However, building a TCR-antigen interaction map has been challenging due to the staggering diversity of TCRs and antigens. Accordingly, highly multiplexed dextramer-TCR binding assays have been recently d...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Adv
Main Authors: Zhang, Wen, Hawkins, Peter G., He, Jing, Gupta, Namita T., Liu, Jinrui, Choonoo, Gabrielle, Jeong, Se W., Chen, Calvin R., Dhanik, Ankur, Dillon, Myles, Deering, Raquel, Macdonald, Lynn E., Thurston, Gavin, Atwal, Gurinder S.
Format: Artigo
Jezik:Inglês
Izdano: American Association for the Advancement of Science 2021
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8121425/
https://ncbi.nlm.nih.gov/pubmed/33990328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abf5835
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