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Controlled release of insulin-like growth factor 1 enhances urethral sphincter function and histological structure in the treatment of female stress urinary incontinence in a rat model

OBJECTIVES: To determine the effects of controlled release of insulin-like growth factor 1 (IGF-1) from alginate-poly-L-ornithine-gelatine (A-PLO-G) microbeads on external urethral sphincter (EUS) tissue regeneration in a rat model of stress urinary incontinence (SUI), as SUI diminishes the quality...

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Detalhes bibliográficos
Publicado no:BJU Int
Main Authors: Yan, Hao, Zhong, Liren, Jiang, Yaodong, Yang, Jian, Deng, Junhong, Wei, Shicheng, Opara, Emmanuel, Atala, Anthony, Mao, Xiangming, Damaser, Margot S., Zhang, Yuanyuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8121163/
https://ncbi.nlm.nih.gov/pubmed/28805303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bju.13985
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