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The Diels‐Alder Approach towards Cannabinoid Derivatives and Formal Synthesis of Tetrahydrocannabinol (THC)

Based on the Diels‐Alder reaction of vinylchromenes with electron‐poor dienophiles, we developed a strategy for the synthesis of tetrahydrocannabinol derivatives. Substituted vinyl chromenes could be converted with several dienophiles to successfully isolate several complex molecules. These molecule...

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Publicat a:ChemistryOpen
Autors principals: Hurrle, Thomas, Gläser, Franziska, Bröhmer, Manuel C., Nieger, Martin, Bräse, Stefan
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8121136/
https://ncbi.nlm.nih.gov/pubmed/33988908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.202000343
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