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Disease Variants of Human Δ(1)-Pyrroline-5-Carboxylate Reductase 2 (PYCR2)
Pyrroline-5-carboxylate reductase (PYCR in humans) catalyzes the final step of L-proline biosynthesis by catalyzing the reduction of L-Δ(1)-pyrroline-5-carboxylate (L-P5C) to L-proline using NAD(P)H as the hydride donor. In humans, three isoforms PYCR1, PYCR2, and PYCR3 are known. Recent genome-wide...
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| Veröffentlicht in: | Arch Biochem Biophys |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8120637/ https://ncbi.nlm.nih.gov/pubmed/33771508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2021.108852 |
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