Targeted inhibition of SIRT6 via engineered exosomes impairs tumorigenesis and metastasis in prostate cancer

The treatment for metastatic castration-resistant prostate cancer patients remains a great challenge in the clinic and continuously demands discoveries of new targets and therapies. Here, we assess the function and therapeutic value of SIRT6 in metastatic castration-resistant prostate cancer. Method...

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Publicado en:Theranostics
Autores principales: Han, Qing, Xie, Qian Rueben, Li, Fan, Cheng, Yirui, Wu, Tingyu, Zhang, Yanshuang, Lu, Xin, Wong, Alice S.T., Sha, Jianjun, Xia, Weiliang
Formato: Artigo
Lenguaje:Inglês
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8120217/
https://ncbi.nlm.nih.gov/pubmed/33995674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.53886
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