DsbA-L Ameliorates Renal Injury Through the AMPK/NLRP3 Inflammasome Signaling Pathway in Diabetic Nephropathy

NLRP3-mediated inflammation is closely related to the pathological progression of diabetic nephropathy (DN). DsbA-L, an antioxidant enzyme, plays a protective role in a variety of diseases by inhibiting ER stress and regulating metabolism. However, the relationship of DsbA-L with inflammation, espec...

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Vydáno v:Front Physiol
Hlavní autoři: Yang, Ming, Luo, Shilu, Jiang, Na, Wang, Xi, Han, Yachun, Zhao, Hao, Xiong, Xiaofen, Liu, Yan, Zhao, Chanyue, Zhu, Xuejing, Sun, Lin
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Physiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8120163/
https://ncbi.nlm.nih.gov/pubmed/33995126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2021.659751
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