Clinical effects of administering leukemia-specific donor T cells to patients with AML/MDS after allogeneic transplant

Relapse after allogeneic hematopoietic stem cell transplantation (HCT) is the leading cause of death in patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). Infusion of unselected donor lymphocytes (DLIs) enhances the graft-versus-leukemia (GVL) effect. However, because the...

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Publicado en:Blood
Main Authors: Lulla, Premal D., Naik, Swati, Vasileiou, Spyridoula, Tzannou, Ifigeneia, Watanabe, Ayumi, Kuvalekar, Manik, Lulla, Suhasini, Carrum, George, Ramos, Carlos A., Kamble, Rammurti, Hill, LaQuisa, Randhawa, Jasleen, Gottschalk, Stephen, Krance, Robert, Wang, Tao, Wu, Mengfen, Robertson, Catherine, Gee, Adrian P., Chung, Betty, Grilley, Bambi, Brenner, Malcolm K., Heslop, Helen E., Vera, Juan F., Leen, Ann M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2021
Assuntos:
Clinical Trials and Observations
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8120140/
https://ncbi.nlm.nih.gov/pubmed/33270816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020009471
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