Hippocampal CA3 transcriptional modules associated with granule cell alterations and cognitive impairment in refractory mesial temporal lobe epilepsy patients

In about a third of the patients with epilepsy the seizures are not drug-controlled. The current limitation of the antiepileptic drug therapy derives from an insufficient understanding of epilepsy pathophysiology. In order to overcome this situation, it is necessary to consider epilepsy as a disturb...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bando, Silvia Yumi, Bertonha, Fernanda Bernardi, Pimentel-Silva, Luciana Ramalho, de Oliveira, João Gabriel Mansano, Carneiro, Marco Antonio Duarte, Oku, Mariana Hiromi Manoel, Wen, Hung-Tzu, Castro, Luiz Henrique Martins, Moreira-Filho, Carlos Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8119682/
https://ncbi.nlm.nih.gov/pubmed/33986407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89802-3
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