Characterization of an attenuated SARS-CoV-2 variant with a deletion at the S1/S2 junction of the spike protein

SARS-CoV-2 is of zoonotic origin and contains a PRRA polybasic cleavage motif which is considered critical for efficient infection and transmission in humans. We previously reported on a panel of attenuated SARS-CoV-2 variants with deletions at the S1/S2 junction of the spike protein. Here, we chara...

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Publicado no:Nat Commun
Main Authors: Wang, Pui, Lau, Siu-Ying, Deng, Shaofeng, Chen, Pin, Mok, Bobo Wing-Yee, Zhang, Anna Jinxia, Lee, Andrew Chak-Yiu, Chan, Kwok-Hung, Tam, Rachel Chun-Yee, Xu, Haoran, Zhou, Runhong, Song, Wenjun, Liu, Li, To, Kelvin Kai-Wang, Chan, Jasper Fuk-Woo, Chen, Zhiwei, Yuen, Kwok-Yung, Chen, Honglin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8119425/
https://ncbi.nlm.nih.gov/pubmed/33986286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23166-0
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