Mitochondrial Function and Anesthetic Sensitivity in the Mouse Spinal Cord

BACKGROUND. Ndufs4 knockout mice are defective in mitochondrial complex I function and hypersensitive to inhibition of spinal cord-mediated response to noxious stimuli by volatile anesthetics. We hypothesized that, compared to wildtype, synaptic or intrinsic neuronal function is hypersensitive to is...

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Vydáno v:Anesthesiology
Hlavní autoři: Woods, Christian B, Spencer, Kira A, Jung, Sangwook, Worstman, Hailey M, Ramirez, Jan-Marino, Morgan, Philip G, Sedensky, Margaret M
Médium: Artigo
Jazyk:Inglês
Vydáno: 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8119385/
https://ncbi.nlm.nih.gov/pubmed/33909880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000003794
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