Microstructural changes in the left mesocorticolimbic pathway are associated with the comorbid development of fatigue and depression in multiple sclerosis

BACKGROUND AND PURPOSE: Lower reward responsiveness has been associated with fatigue in multiple sclerosis (MS). However, association of MS-related fatigue with damage to the mesocorticolimbic reward pathway (superolateral medial forebrain bundle (slMFB)) has not been assessed. We investigated the a...

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Veröffentlicht in:J Neuroimaging
Hauptverfasser: Palotai, Miklos, Small, Catherine, Makris, Nikolaos, Somes, Nathaniel G., Pinzon, Alfredo Morales, Rathi, Yogesh, Marzullo, Aldo, Levitt, James J., Bakshi, Rohit, Chitnis, Tanuja, Guttmann, Charles R.G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8119307/
https://ncbi.nlm.nih.gov/pubmed/33522683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jon.12832
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