Circulating nuclear DNA structural features, origins, and complete size profile revealed by fragmentomics

To unequivocally address their unresolved intimate structures in blood, we scrutinized the size distribution of circulating cell-free DNA (cfDNA) using whole-genome sequencing (WGS) from both double- and single-strand DNA library preparations (DSP and SSP, n = 7) and using quantitative PCR (Q-PCR, n...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Sanchez, Cynthia, Roch, Benoit, Mazard, Thibault, Blache, Philippe, Dache, Zahra Al Amir, Pastor, Brice, Pisareva, Ekaterina, Tanos, Rita, Thierry, Alain R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2021
Assuntos:
Technical Advance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8119211/
https://ncbi.nlm.nih.gov/pubmed/33571170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.144561
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