Hypoxia-inducible factor prolyl hydroxylase inhibitor roxadustat (FG-4592) protects against renal ischemia/reperfusion injury by inhibiting inflammation

Hypoxia-induced inflammation is the critical pathological feature of acute kidney injury (AKI). Activation of hypoxia-inducible factor (HIF) signaling is considered as a central mechanism of body adapting to hypoxia. Hypoxia-inducible factor prolyl hydroxylase inhibitor FG-4592 (Roxadustat) is a fir...

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Bibliografiska uppgifter
I publikationen:Ren Fail
Huvudupphovsmän: Miao, A-Feng, Liang, Jian-Xiang, Yao, Lei, Han, Jun-Ling, Zhou, Li-Juan
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 2021
Ämnen:
Laboratory Study
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8118507/
https://ncbi.nlm.nih.gov/pubmed/33966598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/0886022X.2021.1915801
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