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Pembrolizumab in unresectable or metastatic MSI-high colorectal cancer: safety and efficacy
INTRODUCTION: Microsatellite instability-high (MSI-H) colorectal cancer (CRC) represents a unique subset of CRC characterized by elevated neoantigen expression and a high degree of intraepithelial T-cell infiltrate. These characteristics make MSI-H tumors particularly susceptible to immune checkpoin...
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| Udgivet i: | Expert Rev Anticancer Ther |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8118165/ https://ncbi.nlm.nih.gov/pubmed/33183114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14737140.2021.1851201 |
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