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Development of Systemic Immune Dysregulation in a Rat Trauma Model of Biomaterial-Associated Infection

Orthopedic biomaterial-associated infections remain a major clinical challenge, with Staphylococcus aureus being the most common pathogen. S. aureus biofilm formation enhances immune evasion and antibiotic resistance, resulting in a local, indolent infection that can persist long-term without sympto...

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Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Vantucci, Casey E., Ahn, Hyunhee, Fulton, Travis, Schenker, Mara L., Pradhan, Pallab, Wood, Levi B., Guldberg, Robert E., Roy, Krishnendu, Willett, Nick J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8117743/
https://ncbi.nlm.nih.gov/pubmed/33069135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2020.120405
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