H3K27M and TERT promoter mutations are poor prognostic factors in surgical cases of adult thalamic high-grade glioma

BACKGROUND: Thalamic high-grade gliomas (HGGs) are rare tumors with a dismal prognosis. H3K27M and telomerase reverse transcriptase promoter (TERTp) mutations reportedly contribute to poor prognoses in HGG cases. We investigated the outcomes of surgically treated adult thalamic HGGs to evaluate the...

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Détails bibliographiques
Publié dans:Neurooncol Adv
Auteurs principaux: Osada, Yoshinari, Saito, Ryuta, Shibahara, Ichiyo, Sasaki, Keisuke, Shoji, Takuhiro, Kanamori, Masayuki, Sonoda, Yukihiko, Kumabe, Toshihiro, Watanabe, Mika, Tominaga, Teiji
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2021
Sujets:
Clinical Investigations
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8117440/
https://ncbi.nlm.nih.gov/pubmed/34013205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab038
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