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H3K27M and TERT promoter mutations are poor prognostic factors in surgical cases of adult thalamic high-grade glioma

BACKGROUND: Thalamic high-grade gliomas (HGGs) are rare tumors with a dismal prognosis. H3K27M and telomerase reverse transcriptase promoter (TERTp) mutations reportedly contribute to poor prognoses in HGG cases. We investigated the outcomes of surgically treated adult thalamic HGGs to evaluate the...

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Publicado en:Neurooncol Adv
Main Authors: Osada, Yoshinari, Saito, Ryuta, Shibahara, Ichiyo, Sasaki, Keisuke, Shoji, Takuhiro, Kanamori, Masayuki, Sonoda, Yukihiko, Kumabe, Toshihiro, Watanabe, Mika, Tominaga, Teiji
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8117440/
https://ncbi.nlm.nih.gov/pubmed/34013205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab038
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