H3K27M and TERT promoter mutations are poor prognostic factors in surgical cases of adult thalamic high-grade glioma

BACKGROUND: Thalamic high-grade gliomas (HGGs) are rare tumors with a dismal prognosis. H3K27M and telomerase reverse transcriptase promoter (TERTp) mutations reportedly contribute to poor prognoses in HGG cases. We investigated the outcomes of surgically treated adult thalamic HGGs to evaluate the...

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Bibliographic Details
Published in:Neurooncol Adv
Main Authors: Osada, Yoshinari, Saito, Ryuta, Shibahara, Ichiyo, Sasaki, Keisuke, Shoji, Takuhiro, Kanamori, Masayuki, Sonoda, Yukihiko, Kumabe, Toshihiro, Watanabe, Mika, Tominaga, Teiji
Format: Artigo
Language:Inglês
Published: Oxford University Press 2021
Subjects:
Clinical Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8117440/
https://ncbi.nlm.nih.gov/pubmed/34013205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab038
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