H3K27M and TERT promoter mutations are poor prognostic factors in surgical cases of adult thalamic high-grade glioma

BACKGROUND: Thalamic high-grade gliomas (HGGs) are rare tumors with a dismal prognosis. H3K27M and telomerase reverse transcriptase promoter (TERTp) mutations reportedly contribute to poor prognoses in HGG cases. We investigated the outcomes of surgically treated adult thalamic HGGs to evaluate the...

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Vydáno v:Neurooncol Adv
Hlavní autoři: Osada, Yoshinari, Saito, Ryuta, Shibahara, Ichiyo, Sasaki, Keisuke, Shoji, Takuhiro, Kanamori, Masayuki, Sonoda, Yukihiko, Kumabe, Toshihiro, Watanabe, Mika, Tominaga, Teiji
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2021
Témata:
Clinical Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8117440/
https://ncbi.nlm.nih.gov/pubmed/34013205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab038
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