Case Report: Immune Checkpoint Inhibitor-Induced Exuberant Tumor Inflammation With Accelerated Clinical Deterioration in Metastatic Renal Cell Carcinoma

Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy. Nivolumab, an anti-PD-1 monoclonal antibody, markedly improved overall survival in advanced renal cell carcinoma (RCC). However, ICIs can rarely trigger massive inflammation, a phenomenon characterized by rapid acceleration in r...

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Vydáno v:Front Oncol
Hlavní autoři: Gopalakrishnan, Dharmesh, Jain, Rohit K., Herbst, Laurie, Sikorski, Marcus, Mandava, Silpa, Azabdaftari, Gissou, Xu, Bo, LeVea, Charles, Robillard, Kevin, Ernstoff, Marc S., George, Saby
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Oncology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8117341/
https://ncbi.nlm.nih.gov/pubmed/33996609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.679177
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