Accounting for Population Structure and Phenotypes From Relatives in Association Mapping for Farm Animals: A Simulation Study

Population structure or genetic relatedness should be considered in genome association studies to avoid spurious association. The most used methods for genome-wide association studies (GWAS) account for population structure but are limited to genotyped individuals with phenotypes. Single-step GWAS (...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Mancin, Enrico, Lourenco, Daniela, Bermann, Matias, Mantovani, Roberto, Misztal, Ignacy
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8117227/
https://ncbi.nlm.nih.gov/pubmed/33995481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2021.642065
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