Effects of APOE ε2 on the Fractional Amplitude of Low-Frequency Fluctuation in Mild Cognitive Impairment: A Study Based on the Resting-State Functional MRI

BACKGROUND: Apolipoprotein E (APOE) ε2 is a protective genetic factor for Alzheimer’s disease (AD). However, the potential interaction effects between the APOE ε2 allele and disease status on the intrinsic brain activity remain elusive. METHODS: We identified 73 healthy control (HC) with APOE ε3/ε3,...

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Vydáno v:Front Aging Neurosci
Hlavní autoři: Liu, Xiaocao, Zeng, Qingze, Luo, Xiao, Li, Kaicheng, Hong, Hui, Wang, Shuyue, Guan, Xiaojun, Wu, Jingjing, Zhang, Ruiting, Zhang, Tianyi, Li, Zheyu, Fu, Yanv, Wang, Tao, Wang, Chao, Xu, Xiaojun, Huang, Peiyu, Zhang, Minming
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8117101/
https://ncbi.nlm.nih.gov/pubmed/33994988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2021.591347
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