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Chronic Toxoplasma gondii Infection Alleviates Experimental Autoimmune Encephalomyelitis by the Immune Regulation Inducing Reduction in IL-17A/Th17 Via Upregulation of SOCS3

Experimental autoimmune encephalomyelitis (EAE) is a mouse model of multiple sclerosis (MS), a demyelinating autoimmune disease caused by the infiltration of a harmful autoreactive Th1 and Th17 cells. To mitigate MS, which is impossible to cure with medication only, immunomodulatory interventions th...

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Détails bibliographiques
Publié dans:Neurotherapeutics
Auteurs principaux: Ham, Do-Won, Kim, Sang-Gyun, Seo, Seung-Hwan, Shin, Ji-Hun, Lee, Sang Hyung, Shin, Eun-Hee
Format: Artigo
Langue:Inglês
Publié: Springer International Publishing 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8116467/
https://ncbi.nlm.nih.gov/pubmed/33205383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-020-00957-9
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