Role of Tryptophan 38 in Loading Substrate Chain into the Active-site Tunnel of Cellobiohydrolase I from Trichoderma reesei

Cellobiohydrolase I from Trichoderma reesei ( Tr Cel7A) is one of the best-studied cellulases, exhibiting high activity towards crystalline cellulose. Tryptophan residues at subsites -7 and -4 (Trp40 and Trp38 respectively) are located at the entrance and middle of the tunnel-like active site of Tr...

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Bibliografiske detaljer
Udgivet i:J Appl Glycosci (1999)
Main Authors: Nakamura, Akihiko, Kanazawa, Takashi, Furuta, Tadaomi, Sakurai, Minoru, Saloheimo, Markku, Samejima, Masahiro, Koivula, Anu, Igarashi, Kiyohiko
Format: Artigo
Sprog:Inglês
Udgivet: The Japanese Society of Applied Glycoscience 2021
Fag:
Regular Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8116176/
https://ncbi.nlm.nih.gov/pubmed/34354542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5458/jag.jag.JAG-2020_0014
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