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Focal Sleep Spindle Deficits Reveal Focal Thalamocortical Dysfunction and Predict Cognitive Deficits in Sleep Activated Developmental Epilepsy

Childhood epilepsy with centrotemporal spikes (CECTS) is the most common focal epilepsy syndrome, yet the cause of this disease remains unknown. Now recognized as a mild epileptic encephalopathy, children exhibit sleep-activated focal epileptiform discharges and cognitive difficulties during the act...

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Publicado en:J Neurosci
Main Authors: Kramer, Mark A., Stoyell, Sally M., Chinappen, Dhinakaran, Ostrowski, Lauren M., Spencer, Elizabeth R., Morgan, Amy K., Emerton, Britt Carlson, Jing, Jin, Westover, M. Brandon, Eden, Uri T., Stickgold, Robert, Manoach, Dara S., Chu, Catherine J.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8115887/
https://ncbi.nlm.nih.gov/pubmed/33468567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2009-20.2020
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