Relationship Between Blood Pressure and Incident Cardiovascular Disease: Linear and Nonlinear Mendelian Randomization Analyses

Observational studies exploring whether there is a nonlinear effect of blood pressure on cardiovascular disease (CVD) risk are hindered by confounding. This limitation can be overcome by leveraging randomly allocated genetic variants in nonlinear Mendelian randomization analyses. Based on their asso...

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Detalhes bibliográficos
Publicado no:Hypertension
Main Authors: Malik, Rainer, Georgakis, Marios K., Vujkovic, Marijana, Damrauer, Scott M., Elliott, Paul, Karhunen, Ville, Giontella, Alice, Fava, Cristiano, Hellwege, Jacklyn N., Shuey, Megan M., Edwards, Todd L., Rogne, Tormod, Åsvold, Bjørn O., Brumpton, Ben M., Burgess, Stephen, Dichgans, Martin, Gill, Dipender
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2021
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8115430/
https://ncbi.nlm.nih.gov/pubmed/33813844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.120.16534
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