Relationship Between Blood Pressure and Incident Cardiovascular Disease: Linear and Nonlinear Mendelian Randomization Analyses

Observational studies exploring whether there is a nonlinear effect of blood pressure on cardiovascular disease (CVD) risk are hindered by confounding. This limitation can be overcome by leveraging randomly allocated genetic variants in nonlinear Mendelian randomization analyses. Based on their asso...

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Bibliografiske detaljer
Udgivet i:Hypertension
Main Authors: Malik, Rainer, Georgakis, Marios K., Vujkovic, Marijana, Damrauer, Scott M., Elliott, Paul, Karhunen, Ville, Giontella, Alice, Fava, Cristiano, Hellwege, Jacklyn N., Shuey, Megan M., Edwards, Todd L., Rogne, Tormod, Åsvold, Bjørn O., Brumpton, Ben M., Burgess, Stephen, Dichgans, Martin, Gill, Dipender
Format: Artigo
Sprog:Inglês
Udgivet: Lippincott Williams & Wilkins 2021
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8115430/
https://ncbi.nlm.nih.gov/pubmed/33813844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.120.16534
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