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Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma

Immune checkpoint blockade (ICB) results in durable disease control in a subset of patients with advanced renal cell carcinoma (RCC), but mechanisms driving resistance are poorly understood. We characterize the single-cell transcriptomes of cancer and immune cells from metastatic RCC patients before...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Cancer Cell
Main Authors: Bi, Kevin, He, Meng Xiao, Bakouny, Ziad, Kanodia, Abhay, Napolitano, Sara, Wu, Jingyi, Grimaldi, Grace, Braun, David A., Cuoco, Michael S., Mayorga, Angie, DelloStritto, Laura, Bouchard, Gabrielle, Steinharter, John, Tewari, Alok K., Vokes, Natalie I., Shannon, Erin, Sun, Maxine, Park, Jihye, Chang, Steven L., McGregor, Bradley A., Haq, Rizwan, Denize, Thomas, Signoretti, Sabina, Guerriero, Jennifer L., Vigneau, Sébastien, Rozenblatt-Rosen, Orit, Rotem, Asaf, Regev, Aviv, Choueiri, Toni K., Van Allen, Eliezer M.
פורמט: Artigo
שפה:Inglês
יצא לאור: Cell Press 2021
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC8115394/
https://ncbi.nlm.nih.gov/pubmed/33711272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2021.02.015
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