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Symmetrically dimethylated histone H3R2 promotes global transcription during minor zygotic genome activation in mouse pronuclei

Paternal genome reprogramming, such as protamine–histone exchange and global DNA demethylation, is crucial for the development of fertilised embryos. Previously, our study showed that one of histone arginine methylation, asymmetrically dimethylated histone H3R17 (H3R17me2a), is necessary for epigene...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Morita, Kohtaro, Hatanaka, Yuki, Ihashi, Shunya, Asano, Masahide, Miyamoto, Kei, Matsumoto, Kazuya
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8115239/
https://ncbi.nlm.nih.gov/pubmed/33980975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89334-w
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