Bacteroides Fragilis Polysaccharide A Ameliorates Abnormal Voriconazole Metabolism Accompanied With the Inhibition of TLR4/NF-κB Pathway

The antifungal agent voriconazole (VRC) exhibits extreme inter-individual and intra-individual variation in terms of its clinical efficacy and toxicity. Inflammation, as reflected by C-reactive protein (CRP) concentrations, significantly affects the metabolic ratio and trough concentrations of voric...

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Опубликовано в: :Front Pharmacol
Главные авторы: Wang, Xiaokang, Ye, Chunxiao, Xun, Tianrong, Mo, Liqian, Tong, Yong, Ni, Wensi, Huang, Suping, Liu, Bin, Zhan, Xia, Yang, Xixiao
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2021
Предметы:
Pharmacology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8115215/
https://ncbi.nlm.nih.gov/pubmed/33995087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.663325
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