Estrogen Signaling and Portopulmonary Hypertension: The Pulmonary Vascular Complications of Liver Disease Study (PVCLD2)

OBJECTIVES: Portopulmonary hypertension (POPH) was previously associated with a single nucleotide polymorphism (SNP) rs7175922 in aromatase (CYP19A1). We sought to determine if genetic variants and metabolites in the estrogen signaling pathway are associated with POPH. METHODS: We performed a multic...

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Publicado en:Hepatology
Autores principales: Al-Naamani, Nadine, Krowka, Michael J., Forde, Kimberly A., Krok, Karen L., Feng, Rui, Heresi, Gustavo A., Dweik, Raed A., Bartolome, Sonja, Bull, Todd M., Roberts, Kari E., Austin, Eric D., Hemnes, Anna R., Patel, Mamta J., Oh, Jae K., Lin, Grace, Doyle, Margaret F., Denver, Nina, Andrew, Ruth, MacLean, Margaret R., Fallon, Michael B., Kawut, Steven M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8115214/
https://ncbi.nlm.nih.gov/pubmed/32407592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.31314
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