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Engineered human myocardium with local release of angiogenic proteins improves vascularization and cardiac function in injured rat hearts

Heart regeneration after myocardial infarction requires new cardiomyocytes and a supportive vascular network. Here, we evaluate the efficacy of localized delivery of angiogenic factors from biomaterials within the implanted muscle tissue to guide growth of a more dense, organized, and perfused vascu...

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Publicat a:Biomaterials
Autors principals: Munarin, Fabiola, Kant, Rajeev J., Rupert, Cassady E., Khoo, Amelia, Coulombe, Kareen L.K.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8115013/
https://ncbi.nlm.nih.gov/pubmed/32388033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2020.120033
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