LRP6 downregulation promotes cardiomyocyte proliferation and heart regeneration

The adult mammalian heart is thought to be a terminally differentiated organ given the postmitotic nature of cardiomyocytes. Consequently, the potential for cardiac repair through cardiomyocyte proliferation is extremely limited. Low-density lipoprotein receptor-related protein 6 (LRP6) is a Wnt co-...

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Detalhes bibliográficos
Publicado no:Cell Res
Main Authors: Wu, Yahan, Zhou, Liping, Liu, Hongyu, Duan, Ran, Zhou, Huixing, Zhang, Fulei, He, Xiaoyu, Lu, Dongbo, Xiong, Ke, Xiong, Maolin, Zhuang, Jinzhu, Liu, Yi, Li, Li, Liang, Dandan, Chen, Yi-Han
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Singapore 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8114926/
https://ncbi.nlm.nih.gov/pubmed/32973339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-020-00411-7
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