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Conjugate of Doxorubicin to Albumin-Binding Peptide Outperforms Aldoxorubicin

Short circulation time and off-target toxicity are the main challenges faced by small-molecule chemotherapeutics. To overcome these shortcomings, an albumin-binding peptide conjugate of chemotherapeutics is developed that binds specifically to endogenous albumin and harnesses its favorable pharmacok...

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Detalhes bibliográficos
Publicado no:Small
Main Authors: Yousefpour, Parisa, Ahn, Lucie, Tewksbury, Joel, Saha, Soumen, Costa, Simone A., Bellucci, Joseph J., Li, Xinghai, Chilkoti, Ashutosh
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8114561/
https://ncbi.nlm.nih.gov/pubmed/30756483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/smll.201804452
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