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Capsazepine decreases corneal pain syndrome in severe dry eye disease

BACKGROUND: Dry eye disease (DED) is a multifactorial disease of the ocular surface accompanied by neurosensory abnormalities. Here, we evaluated the effectiveness of transient receptor potential vanilloid-1 (TRPV1) blockade to alleviate ocular pain, neuroinflammation, and anxiety-like behavior asso...

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Publicat a:J Neuroinflammation
Autors principals: Fakih, Darine, Guerrero-Moreno, Adrian, Baudouin, Christophe, Goazigo, Annabelle Réaux-Le, Parsadaniantz, Stéphane Mélik
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8114509/
https://ncbi.nlm.nih.gov/pubmed/33975636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-021-02162-7
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