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Stimulation of α7 Nicotinic Acetylcholine Receptor by Nicotine Suppresses Decidual M1 Macrophage Polarization Against Inflammation in Lipopolysaccharide-Induced Preeclampsia-Like Mouse Model

Changes in decidual macrophage polarization affect local inflammatory microenvironment and lead to adverse pregnancy outcomes. However, the regulatory mechanism of macrophage polarization in preeclampsia (PE) remains unclear. In this study, we found that α7nAChR expression was significantly down-reg...

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Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Han, Xinjia, Li, Wei, Li, Ping, Zheng, Zheng, Lin, Baohua, Zhou, Bei, Guo, Kaimin, He, Ping, Yang, Jinying
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8113862/
https://ncbi.nlm.nih.gov/pubmed/33995360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.642071
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