Engineering hiPSC-CM and hiPSC-EC laden 3D nanofibrous splenic hydrogel for improving cardiac function through revascularization and remuscularization in infarcted heart

Cell therapy has been a promising strategy for cardiac repair after myocardial infarction (MI), but a poor ischemic environment and low cell delivery efficiency remain significant challenges. The spleen serves as a hematopoietic stem cell niche and secretes cardioprotective factors after MI, but it...

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Publicado en:Bioact Mater
Autores principales: Guan, Ge, Huo, Da, Li, Yanzhao, Zhao, Xiaolin, Li, Yinghao, Qin, Zhongliang, Sun, Dayu, Yang, Guanyuan, Yang, Mingcan, Tan, Ju, Zeng, Wen, Zhu, Chuhong
Formato: Artigo
Lenguaje:Inglês
Publicado: KeAi Publishing 2021
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8113784/
https://ncbi.nlm.nih.gov/pubmed/33997517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bioactmat.2021.04.010
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