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Three-Dimensional Model of Sub-Plasmalemmal Ca(2+) Microdomains Evoked by the Interplay Between ORAI1 and InsP(3) Receptors

Ca(2+) signaling plays an essential role in T cell activation, which is a key step to start an adaptive immune response. During the transition from a quiescent to a fully activated state, Ca(2+) microdomains characterized by reduced spatial and temporal extents are observed in the junctions between...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Gil, Diana, Guse, Andreas H., Dupont, Geneviève
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8113648/
https://ncbi.nlm.nih.gov/pubmed/33995380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.659790
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