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Case Report: Aicardi-Goutières Syndrome Caused by Novel TREX1 Variants

TREX1 (three prime repair exonuclease 1) gene encodes DNA 3′ end repair exonuclease that plays an important role in DNA repair. Mutations in TREX1 gene have been identified as the cause of a rare autoimmune neurological disease, Aicardi-Goutières syndrome (AGS). Here, we report an AGS case of a 6-mo...

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Detalhes bibliográficos
Publicado no:Front Pediatr
Main Authors: Wu, De, Fang, Liwei, Huang, Ting, Ying, Songcheng
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8113616/
https://ncbi.nlm.nih.gov/pubmed/33996686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fped.2021.634281
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