Knockout RAGE alleviates cardiac fibrosis through repressing endothelial-to-mesenchymal transition (EndMT) mediated by autophagy

Endothelial-to-mesenchymal transition (EndMT) has been shown to contribute to cardiac fibrosis and heart failure (HF). Recent studies have demonstrated that EndMT is regulated by autophagy, and we previously showed suppression of excessive autophagy and alleviation of cardiac fibrosis in HF mice wit...

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Bibliographic Details
Published in:Cell Death Dis
Main Authors: Zhang, Lu, He, Jiaqi, Wang, Junyan, Liu, Jing, Chen, Zixin, Deng, Bo, Wei, Lan, Wu, Hanqin, Liang, Birong, Li, Huan, Huang, Yusheng, Lu, Lu, Yang, Zhongqi, Xian, Shaoxiang, Wang, Lingjun
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8113558/
https://ncbi.nlm.nih.gov/pubmed/33976108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03750-4
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