Knockout RAGE alleviates cardiac fibrosis through repressing endothelial-to-mesenchymal transition (EndMT) mediated by autophagy

Endothelial-to-mesenchymal transition (EndMT) has been shown to contribute to cardiac fibrosis and heart failure (HF). Recent studies have demonstrated that EndMT is regulated by autophagy, and we previously showed suppression of excessive autophagy and alleviation of cardiac fibrosis in HF mice wit...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Zhang, Lu, He, Jiaqi, Wang, Junyan, Liu, Jing, Chen, Zixin, Deng, Bo, Wei, Lan, Wu, Hanqin, Liang, Birong, Li, Huan, Huang, Yusheng, Lu, Lu, Yang, Zhongqi, Xian, Shaoxiang, Wang, Lingjun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8113558/
https://ncbi.nlm.nih.gov/pubmed/33976108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03750-4
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