Knockout RAGE alleviates cardiac fibrosis through repressing endothelial-to-mesenchymal transition (EndMT) mediated by autophagy

Endothelial-to-mesenchymal transition (EndMT) has been shown to contribute to cardiac fibrosis and heart failure (HF). Recent studies have demonstrated that EndMT is regulated by autophagy, and we previously showed suppression of excessive autophagy and alleviation of cardiac fibrosis in HF mice wit...

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Publicado en:Cell Death Dis
Autores principales: Zhang, Lu, He, Jiaqi, Wang, Junyan, Liu, Jing, Chen, Zixin, Deng, Bo, Wei, Lan, Wu, Hanqin, Liang, Birong, Li, Huan, Huang, Yusheng, Lu, Lu, Yang, Zhongqi, Xian, Shaoxiang, Wang, Lingjun
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2021
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8113558/
https://ncbi.nlm.nih.gov/pubmed/33976108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03750-4
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