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Alteration of the cholinergic system and motor deficits in cholinergic neuron-specific Dyt1 knockout mice

Dystonia is a neurological movement disorder characterized by sustained or intermittent muscle contractions, repetitive movement, and sometimes abnormal postures. DYT1 dystonia is one of the most common genetic dystonias, and most patients carry heterozygous DYT1 ΔGAG mutations causing a loss of a g...

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Detalhes bibliográficos
Publicado no:Neurobiol Dis
Main Authors: Liu, Yuning, Xing, Hong, Sheng, Wanhui, Singh, Kyle N, Korkmaz, Alexandra G., Comeau, Caroline, Anika, Maisha, Ernst, Alexis, Yokoi, Fumiaki, Vaillancourt, David E., Frazier, Charles J., Li, Yuqing
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8113083/
https://ncbi.nlm.nih.gov/pubmed/33757902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2021.105342
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