Utilization of redox modulating small molecules that selectively act as pro-oxidants in cancer cells to open a therapeutic window for improving cancer therapy

There is a rapidly growing body of literature supporting the notion that differential oxidative metabolism in cancer versus normal cells represents a metabolic frailty that can be exploited to open a therapeutic window into cancer therapy. These cancer cell-specific metabolic frailties may be amenab...

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Veröffentlicht in:Redox Biol
Hauptverfasser: Petronek, M.S., Stolwijk, J.M., Murray, S.D., Steinbach, E.J., Zakharia, Y., Buettner, G.R., Spitz, D.R., Allen, B.G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2021
Schlagworte:
Articles from the Special Issue on Redox Modulation of Cancer Heterogeneity, Therapeutic Resistance and Immunotherapy Efficacy; Edited by Dr. Anita Hjelmeland
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8113052/
https://ncbi.nlm.nih.gov/pubmed/33485837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2021.101864
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