Redox regulation of the insulin signalling pathway

The peptide hormone insulin is a key regulator of energy metabolism, proliferation and survival. Binding of insulin to its receptor activates the PI3K/AKT signalling pathway, which mediates fundamental cellular responses. Oxidants, in particular H(2)O(2), have been recognised as insulin-mimetics. Tr...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Lennicke, Claudia, Cochemé, Helena M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Articles from the Special Issue on Low Molecular Weight Thiols: Lessons Learned and New Perspectives; Edited by Dr. Barry Halliwell and Dr. Ivan Gout
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8113030/
https://ncbi.nlm.nih.gov/pubmed/33893069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2021.101964
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