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Involvement of circRNAs in Proinflammatory Cytokines-Mediated β-Cell Dysfunction

AIM: During the initial stage of type 1 diabetes, prolonged exposure of pancreatic β-cell to proinflammatory cytokines such as IL-1β, TNF-α, and IFN-γ results in a decreased capacity to produce and release insulin, as well as cell loss by apoptosis. Circular RNAs (circRNAs) are a new class of endoge...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Wang, Zhen, Deng, Chao, Zheng, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8112919/
https://ncbi.nlm.nih.gov/pubmed/34054343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/5566453
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