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The role of sigma 1 receptor in organization of endoplasmic reticulum signaling microdomains

Sigma 1 receptor (S1R) is a 223-amino-acid-long transmembrane endoplasmic reticulum (ER) protein. S1R modulates activity of multiple effector proteins and is a well-established drug target. However, signaling functions of S1R in cells are poorly understood. Here, we test the hypothesis that biologic...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Zhemkov, Vladimir, Ditlev, Jonathon A, Lee, Wan-Ru, Wilson, Mikaela, Liou, Jen, Rosen, Michael K, Bezprozvanny, Ilya
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8112866/
https://ncbi.nlm.nih.gov/pubmed/33973848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.65192
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