Therapy with lopinavir/ritonavir and hydroxychloroquine is associated with acute kidney injury in COVID-19 patients

BACKGROUND: Acute kidney injury (AKI) is an independent risk factor for mortality, which affects about 5% of hospitalized coronavirus disease-2019 (COVID-19) patients and up to 25–29% of severely ill COVID-19 patients. Lopinavir/ritonavir and hydroxychloroquine show in vitro activity against severe...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Schneider, Johanna, Jaenigen, Bernd, Wagner, Dirk, Rieg, Siegbert, Hornuss, Daniel, Biever, Paul M., Kern, Winfried V., Walz, Gerd
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2021
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8112697/
https://ncbi.nlm.nih.gov/pubmed/33974624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0249760
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