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Designing and Development of a Tandem Bivalent Nanobody against VEGF(165)

BACKGROUND: Inhibition of angiogenesis using monoclonal antibodies is an effective strategy in cancer therapy. However, they could not penetrate sufficiently into solid tumors. Antibody fragments have solved this issue. However, they suffer from short in vivo half-life. In the current study, a tande...

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Bibliografiske detaljer
Udgivet i:Avicenna J Med Biotechnol
Main Authors: Khodabakhsh, Farnaz, Salimian, Morteza, Ziaee, Pardis, Kazemi-Lomedasht, Fatemeh, Behdani, Mahdi, Ahangari Cohan, Reza
Format: Artigo
Sprog:Inglês
Udgivet: Avicenna Research Institute 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8112138/
https://ncbi.nlm.nih.gov/pubmed/34012520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18502/ajmb.v13i2.5519
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