A Fc-Engineering approach to define functional humoral correlates of immunity against Ebola virus

Protective Ebola virus (EBOV) antibodies have neutralizing activity and induction of Fc-mediated innate immune effector functions. Efforts to enhance Fc-effector functionality often focus on maximizing antibody-dependent cellular cytotoxicity, yet distinct combinations of functions may be critical f...

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Bibliografiset tiedot
Julkaisussa:Immunity
Päätekijät: Gunn, Bronwyn M., Lu, Richard, Slein, Matthew D., Ilinykh, Philipp A., Huang, Kai, Atyeo, Caroline, Schendel, Sharon L., Kim, Jiyoung, Cain, Caitlin, Roy, Vicky, Suscovich, Todd J., Takada, Ayato, Halfmann, Peter J., Kawaoka, Yoshihiro, Pauthner, Matthias G., Momo, Mambu, Goba, Augustine, Kanneh, Lansana, Andersen, Kristian G., Schieffelin, John S., Grant, Donald, Garry, Robert F., Saphire, Erica Ollmann, Bukreyev, Alexander, Alter, Galit
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2021
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8111768/
https://ncbi.nlm.nih.gov/pubmed/33852832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2021.03.009
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