Sphingosine‐1‐phosphate receptor 3 is implicated in BBB injury via the CCL2‐CCR2 axis following acute intracerebral hemorrhage

BACKGROUND: Intracerebral hemorrhage (ICH) is a catastrophic cerebrovascular disease with high morbidity and mortality. Evidence demonstrated that sphingosine‐1‐phosphate receptor (S1PR) plays a vital role in inflammatory damage via the upregulation of CCL2 expression. However, whether S1PR3 is invo...

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Publicat a:CNS Neurosci Ther
Autors principals: Xu, Dingkang, Gao, Qiang, Wang, Fang, Peng, Qianrui, Wang, Guoqing, Wei, Qingjie, Lei, Shixiong, Zhao, Shengqi, Zhang, Longxiao, Guo, Fuyou
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2021
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8111497/
https://ncbi.nlm.nih.gov/pubmed/33645008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.13626
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