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Capsaicin protects cardiomyocytes against lipopolysaccharide-induced damage via 14-3-3γ-mediated autophagy augmentation

Background: The myocardium is susceptible to lipopolysaccharide (LPS)-induced damage in sepsis, and cardiac dysfunction is a leading cause of mortality in patients with sepsis. The changes in cardiomyocyte autophagy in sepsis and the effects and mechanism of action of capsaicin (Cap) remain unclear....

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Qiao, Yang, Wang, Liang, Hu, Tianhong, Yin, Dong, He, Huan, He, Ming
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8111444/
https://ncbi.nlm.nih.gov/pubmed/33986684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.659015
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